This book explores the role of information systems in modern digital firms, covering technical and behavioral perspectives, global e-business, and social collaboration tools. It examines organizational impacts, ethical concerns, and competitive strategies. Learners gain insights into IT infrastructure, emerging technologies like cloud computing and big data, and cybersecurity threats with protective measures. The course also delves into e-commerce trends, knowledge management, artificial intelligence, and data-driven decision-making. Finally, it introduces system development methodologies, including agile and object-oriented approaches, equipping students with essential skills to navigate and innovate in the digital business landscape.