Please wait...
Toll Free: 1800-1234-070, Ph. No.: +91-9711224068
AkiNik Publications
  1. Home
  2. chevron_right
  3. Book

Multidisciplinary Trends in Research

Multidisciplinary Trends in Research


₹ 780


Chief Editor:Dr. Garima Agarwal and Dr. Suyesha Singh
Paperback ISBN:978-93-5570-013-1
Publisher:AkiNik Publications
Language:English
Pages:173
Publication Year:2021
Binding:Paperback
DOI:https://doi.org/10.22271/ed.book.1391

Price Details
Amount₹ 780

Availabilityin stock
Payable Amount₹ 780

This Book is Indexed in:

Indexed in Crossref Indexed in Dimensions Indexed in Research Access

Description

This book explores the crucial role of computational molecular modeling in the discovery and development of pharmaceuticals, particularly focusing on the synthesis and biological applications of heterocyclic compounds. Heterocycles, found in numerous natural drugs, are integral to drug design due to their versatile chemical structures and biological activities. The book highlights cutting-edge research on azomethine ylide chemistry and 1,3-dipolar cycloadditions, offering in-depth theoretical insights into the synthesis of nitrogen-containing heterocycles. With a focus on computational methods such as semi-empirical molecular orbital studies, this work presents a powerful approach for advancing drug discovery and understanding molecular interactions.

Abstract

Computational molecular modeling is a powerful tool for advancing drug design and understanding the mechanisms of molecular recognition. This book delves into the significance of heterocyclic compounds, particularly in the pharmaceutical and agrochemical industries, for their diverse biological activities. It focuses on the synthesis of bioactive spiroheterocycles through 1,3-dipolar cycloaddition reactions, using azomethine ylides derived from acenaphthenequinone and thiazolidine-2-carboxylic acid. Theoretical calculations, including semi-empirical molecular orbital methods, are employed to study the stereochemistry and reactivity of these compounds. The work underscores the role of computational modeling in optimizing drug discovery and enhancing molecular design.

Reviews

5.0

1 reviews





Dr. Meenal Deshmukh
  November 12, 2024

Well-written and informative, though certain sections felt a bit repetitive.

AkiNik Publications
AkiNik Publications Phone: +91-9911215212