Description
This book explores the crucial role of computational molecular modeling in the discovery and development of pharmaceuticals, particularly focusing on the synthesis and biological applications of heterocyclic compounds. Heterocycles, found in numerous natural drugs, are integral to drug design due to their versatile chemical structures and biological activities. The book highlights cutting-edge research on azomethine ylide chemistry and 1,3-dipolar cycloadditions, offering in-depth theoretical insights into the synthesis of nitrogen-containing heterocycles. With a focus on computational methods such as semi-empirical molecular orbital studies, this work presents a powerful approach for advancing drug discovery and understanding molecular interactions.
